Scott Ulrich

Scott Ulrich

Associate Professor, Department of Chemistry
Faculty, School of Humanities and Sciences
Faculty, Biochemistry
Faculty, Premed Option

Specialty:Organic and Biological Chemistry
Phone:(607) 274-7977
E-mail:sulrich@ithaca.edu
Office:352A Ctr for Natural Sciences
Ithaca, NY 14850

Fall 2019 Courses

Organic Chemistry II

Principles of Chemistry lab

Research in Biological Chemistry

There are several projects ongoing in the lab, all of which involve designing and synthesizing molecules to elucidate or control biological systems.  Undergraduate students learn various techniques including organic synthesis, PCR and cloning, protein purification, and enzymology.

Our lab is supported by a grant from the National Institutes of Health.

Budin N, Higgins EH, DiBernardo A, Raab C, Li C, Ulrich SM.  "Efficient synthesis of the ketone body ester (R)-3-hydroxybutyryl-(R)-3-hydroxybutyrate and its (S,S) enantiomer" Bioorganic Chemistry Volume 80, October 2018, Pages 560-564 link

Stalnecker CA, Ulrich SM, Li Y, Ramachandran S, McBrayer MK, DeBerardinis RJ, Cerione RA, Erickson JW. "Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells." Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):394-9.

Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, Grueter CA, Lim H, Saunders LR, Stevens RD, Newgard CB, Farese RV Jr, de Cabo R, Ulrich S, Akassoglou K, Verdin E.   "Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor."  Science. 2013 Jan 11;339(6116):211-4 link

Swem L, Swem D, O'Loughlin C*, Gatmaitman R*, Ulrich SM, Bassler B.  A Quorum Sensing Antagonist that Targets Both Membrane-Bound and Cytoplasmic Receptors Controls Bacterial Pathogenicity  Molecular Cell  35 (2) 143-153, 31 July 2009 link

KrennHrubec K, Marshal B, Hedglin M, Verdin E and Ulrich SM. "Design and Evaluation of Linkerless Hydroxamic Acids and Selective HDAC8 Inhibitors" 2007 March 30 Bioorganic and Medicinal Chemistry Letters link

 

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