Jean Hardwick

Jean Hardwick

Dana Professor, Department of Biology
Faculty, School of Humanities and Sciences
Faculty, Biochemistry
Faculty, Honors Program
Faculty, Premed Option

Publications

Recent Publications (students are noted):

Beaumont, Eric, Southerland, E. Marie, Hardwick, Jean C., Wright, Gary L., Ryan, Shannon ('12) , KenKnight, Bruce H., Armour, J.A., and Ardell, JeffreyL. (2015).  Vagus nerve stimulation mitigates intrinsic cardiac neuronal and adverse myocyte remodeling post myocardial infarction. American Journal of Physiology, 309: H1198-11206. *Selected for APSelect doi: 10.1152/ajpheart.00393.2015. View the Abstract Here

Hardwick, Jean C., Ryan, Shannon E. ('12), Powers, Emily N. ('15), Southerland, E. Marie, and Ardell, Jeffrey L. (2015) Angiotensin receptors alter myocardial infarction-induced remodeling of the guinea pig cardiac plexus.  American Journal of Physiology, 309: R178-188. doi: 10.1152/ajpregu.00004.2015 View the Abstract Here

Hardwick, Jean C., Johnson, Bruce R., Ramirez, Julio J., and Wiertelak, Eric P. (2015).  Proceedings of the Faculty for Undergraduate Neuroscience Workshops at Ithaca College, Ithaca, NY July 30 – Aug 3 2014.  J. Undergrad. Neurosci. Educ. 13: E9-E10. View the Proceedings here 

Jean C. Hardwick, Shannon E. Ryan (’12), Eric Beaumont, Jeffrey L. Ardell, E. Marie Southerland, Dynamic remodeling of the guinea pig intrinsic cardiac plexus induced by chronic myocardial infarction, Autonomic Neuroscience, Available online 31 October 2013, ISSN 1566-0702, http://dx.doi.org/10.1016/j.autneu.2013.10.008.

Merriam, L.A, Baran, C.N. ('08), Girard, B., Hardwick, J.C., May, V., and Parsons, R.L. (2013). PAC1 receptor internalization and endosomal signaling mediate the PACAP-induced increase in guinea pig neuron excitability.  Journal of Neuroscience, 6 March 2013, 33(10): 4614-4622.  View the article

Jean C. Hardwick, E. Marie Southerland, Allison E. Girasole ('10), Shannon E. Ryan ('12), Sara Negrotto, and Jeffrey L. Ardell. (2012). Remodeling of intrinsic cardiac neurons: effects of β-adrenergic receptor blockade in guinea pig models of chronic heart disease. Am J Physiol Regul Integr Comp Physiol. 2012 Nov;303(9):R950-8. doi: 10.1152/ajpregu.00223.2012. Epub 2012 Aug 29.  View the abstract here.

Michael Kerchner, Jean C. Hardwick, and Janice E. Thornton. Identifying and Using "Core Competencies" to Help Design and Assess Undergraduate Neuroscience Curricula. The Journal of Undergraduate Neuroscience Education (JUNE), Fall 2012, 11(1):A27-A37. View the PDF here.

Allison E. Girasole ('10), Christopher P. Palmer ('11), Samantha L. Corrado ('11), E. Marie Southerland, Jeffrey L. Ardell, and Jean D Hardwick (2011).  Angiotensin II potentiates adrenergic and muscarinic modulation of guinea pig intracardiac neurons.  American Journal of Physiology. 301: R1391-1399. View the abstract here.

Hardwick, J.C. and Smith, J. (2010). Undergraduate Neuroscience Faculty: Results from a Survey of Faculty for Undergraduate Neuroscience Members. Journal of Undergraduate Neuroscience Education.8(2): A101-107.  View the PDF here.

Jean C. Hardwick, Caitlin N. Baran ('08), , E. Marie Southerland and Jeffrey L. Ardell. (2009).  Remodeling of the guinea pig intrinsic cardiac plexus with chronic pressure overload, American Journal of Physiology Regulatory, Integrative, and Comparative Physiology, 297: R859-R866.

Hardwick, Jean C., Baran, Caitlin N. ('08), Southerland, E. Marie, and Ardell, Jeffery L. (2009). Remodeling of the guinea pig intrinsic cardiac plexus with chronic pressure overload.  American Journal fo Physiology, Regulatory, Integrative, and Comparative Physiology, 297: R859-R866. 

Hardwick, Jean C., Southerland, E. Marie and Ardell, Jeffery L. (2008).  “Chronic myocardial infarction induces phenotypic and functional remodeling in the guinea pig cardiac plexus.” American Journal of Physiology, Regulatory, Integrative, and Comparative Physiology, 295: R1926-R1933.

Hardwick, J.C., Kotarski, A.F. ('04), and Powers M.J ('01). (2006) Ionic mechanisms of histamine-induced responses in guinea pig intracardiac neurons.  American Journal of Physiology, 290: R241-R250. View the abstract here.

Hardwick, Jean C. (2005). ”Preparing the Next Generation of Neuroscience Educators. “ The Journal of Undergraduate Neuroscience Education (JUNE), 3(2):E3 (Editorial). View the editorial here.

Jelson, G.S. ('02), DeMasi, G.M. ('01), Sager, K.L. ('02) and Hardwick, J.C. (2003).  Modulation of guinea pig intrinsic cardiac neurons by prostaglandins.  American Journal of Physiology 285: R682-R689.

Powers, M.J. ('01), Peterson, B.A. ('01), and Hardwick, J.C. (2001).  Regulation of parasympathetic neurons by mast cells and histamine in the guinea pig heart. Autonomic Neuroscience, 87: 37-45.

Parsons, R.L., Rossignol, T.M., Calupca, M.A., Hardwick, J.C., and Braas, K.M (2001).  PACAP peptides modulate guinea pig cardiac neuron membrane excitability and neuropeptide expression.  Annals of the New York Academy of Science, 921: 202-210.

Schoenfeld, L.K. ('99), Souder, J.A. ('02), and Hardwick, J.C. (2000).  Pituitary adenylate cyclase-activating polypeptide innervation of the mudpuppy cardiac ganglion.  Brain Research 882: 180-190.

Calupca, M.A., Hendricks, G.M., Hardwick, J.C., and Parsons, R.L (1999).  Role of mitochondrial dysfunction in the Ca2+-induced decline of transmitter release at K+-depolarized motor neuron terminals. Journal of Neurophysiology, 18: 498-506.

Braas, K.M., May, V., Harakall, S.A., Hardwick, J.C. and Parsons, R.L. (1998). PACAP modulates parasympathetic neuron excitability in guinea pig cardiac ganglia.  Journal of Neuroscience, 18: 9766-9779.

Hardwick, J.C., Mawe, G.M., and Parsons, R.L. (1997). Tachykinin-induced activation of non- specific cation conductance via NK3 neurokinin receptors in guinea-pig intracardiac neurones. Journal of Physiology, 504: 65-74.

Hardwick, J.C. and Parsons, R.L. (1996). Activation of the protein phosphatase calcineurin during carbachol exposure decreases the extent of recovery from end-plate desensitization. Journal of Neurophysiology, 76: 3609-3616.

Hardwick, J.C., Mawe, G.M, and Parsons, R.L. (1995). Evidence of afferent fiber innervation of parasympathetic neurons of the guinea-pig cardiac ganglion. Journal of the Autonomic Nervous System, 53, 166-174.

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